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/ RTSM / IRT

Randomization & Trial Supply Management

AI-native randomization and supply — from design to accountability.

Salvus RTSM handles every complexity of modern trial supply: adaptive randomization, multi-depot inventory, blinded and unblinded role enforcement, expiry management and real-time allocation — with a Supply Copilot that spots shortfalls before they occur.

Key capabilities

Randomization Design Studio

Real-time Treatment Allocation

Blinding & Unblinding

IP Inventory & Expiry Management

Forecasting & Resupply

Accountability & Reconciliation

2,840

Randomizations this month

99.97%

Allocation uptime

34

Depots managed

< 2s

Allocation response time

What it does

All the capability, none of the complexity.

Salvus RTSM handles every complexity of modern trial supply: adaptive randomization, multi-depot inventory, blinded and unblinded role enforcement, expiry management and real-time allocation — with a Supply Copilot that spots shortfalls before they occur.

01 Randomization Design Studio

Simple, stratified, minimization, adaptive and block designs. Multi-arm and factorial layouts. Import or generate lists with full audit trail per version.

02 Real-time Treatment Allocation

Sub-second allocation via portal, IVR and API. Idempotent retry safety. Blinding enforced at the data layer — unblinded roles see only what the protocol permits.

03 Blinding & Unblinding

Configurable blinding profiles per role. Emergency unblinding via dual-control workflow with mandatory reason capture, sealed in a permanent audit record.

04 IP Inventory & Expiry Management

Kit tracking from manufacture to patient — per depot, per site. Automated expiry alerts, quarantine actions and destruction records.

05 Forecasting & Resupply

Enrolment-driven demand projection with Monte-Carlo simulation. Resupply triggers fire automatically; Supply Copilot explains recommendations in plain language.

06 Accountability & Reconciliation

Dispensing records, returns and destruction captured at site. Accountability reports generated on demand for regulatory submission and audit.

07 Depot & Distribution Management

Multi-depot routing logic, cold-chain flag support, country-specific import documentation and transfer orders with full chain-of-custody.

08 L0–L4 Automation Levels

Every automated action assigned an autonomy level. Resupply proposals (L2) surface for human approval; allocation decisions (L4) are deterministic rules — never AI inference.

How it works

From day one to every day after.

A typical journey through Randomization & Trial Supply Management — from onboarding to steady-state operations.

1

2

3

4 Design

Configure the randomization scheme, stratification factors, arms and supply rules in the Design Studio. Simulate allocation distributions before going live.

Activate

Load validated randomization lists, activate depots and sites. UAT subjects run end-to-end — allocation, dispensing, and reconciliation — before first patient in.

Operate

Sites allocate and dispense; inventory updates in real time. Supply Copilot monitors stock levels 24/7 and proposes resupply waves for coordinator approval.

Close out

Generate accountability reports, reconcile all kits, document returns and destruction. Lock the randomization database with a full audit package.

See It in Action

Watch Randomization & Trial Supply Management in action.

A guided walkthrough of the key workflows — built for Clinical Trial teams who need to see it to believe it.

.

How to add your demo video

1. Upload the Randomization & Trial Supply Management demo to YouTube.

2. Copy the video ID from the URL — the part after watch?v=

3. In the HTML above, find: data-vid="PASTE_VIDEO_ID_HERE"

4. Replace PASTE_VIDEO_ID_HERE with your actual video ID.

5. Save & deploy — the play button handles the rest automatically.

Integrations

Connects where you need it to.

Randomization & Trial Supply Management is designed to work with the rest of the Salvus platform — and with third-party systems your team already uses.

/ RTSM / IRT

Randomization & Trial Supply Management

AI-native randomization and supply — from design to accountability.

Salvus RTSM handles every complexity of modern trial supply: adaptive randomization, multi-depot inventory, blinded and unblinded role enforcement, expiry management and real-time allocation — with a Supply Copilot that spots shortfalls before they occur.

Key capabilities

Randomization Design Studio

Real-time Treatment Allocation

Blinding & Unblinding

IP Inventory & Expiry Management

Forecasting & Resupply

Accountability & Reconciliation

2,840

Randomizations this month

99.97%

Allocation uptime

34

Depots managed

< 2s

Allocation response time

What it does

All the capability, none of the complexity.

Salvus RTSM handles every complexity of modern trial supply: adaptive randomization, multi-depot inventory, blinded and unblinded role enforcement, expiry management and real-time allocation — with a Supply Copilot that spots shortfalls before they occur.

01

Randomization Design Studio

Simple, stratified, minimization, adaptive and block designs. Multi-arm and factorial layouts. Import or generate lists with full audit trail per version.

02

Real-time Treatment Allocation

Sub-second allocation via portal, IVR and API. Idempotent retry safety. Blinding enforced at the data layer — unblinded roles see only what the protocol permits.

03

Blinding & Unblinding

Configurable blinding profiles per role. Emergency unblinding via dual-control workflow with mandatory reason capture, sealed in a permanent audit record.

04

IP Inventory & Expiry Management

Kit tracking from manufacture to patient — per depot, per site. Automated expiry alerts, quarantine actions and destruction records.

05

Forecasting & Resupply

Enrolment-driven demand projection with Monte-Carlo simulation. Resupply triggers fire automatically; Supply Copilot explains recommendations in plain language.

06

Accountability & Reconciliation

Dispensing records, returns and destruction captured at site. Accountability reports generated on demand for regulatory submission and audit.

07

Depot & Distribution Management

Multi-depot routing logic, cold-chain flag support, country-specific import documentation and transfer orders with full chain-of-custody.

08

L0–L4 Automation Levels

Every automated action assigned an autonomy level. Resupply proposals (L2) surface for human approval; allocation decisions (L4) are deterministic rules — never AI inference.

How it works

From day one to every day after.

A typical journey through Randomization & Trial Supply Management — from onboarding to steady-state operations.

1

2

3

4

Design

Configure the randomization scheme, stratification factors, arms and supply rules in the Design Studio. Simulate allocation distributions before going live.

Activate

Load validated randomization lists, activate depots and sites. UAT subjects run end-to-end — allocation, dispensing, and reconciliation — before first patient in.

Operate

Sites allocate and dispense; inventory updates in real time. Supply Copilot monitors stock levels 24/7 and proposes resupply waves for coordinator approval.

Close out

Generate accountability reports, reconcile all kits, document returns and destruction. Lock the randomization database with a full audit package.

See It in Action

Watch Randomization & Trial Supply Management in action.

A guided walkthrough of the key workflows — built for Clinical Trial teams who need to see it to believe it.

.

How to add your demo video

Integrations

Connects where you need it to.

Randomization & Trial Supply Management is designed to work with the rest of the Salvus platform — and with third-party systems your team already uses.

CTMS

Protocol, sites and milestone context

EDC

Visit confirmation & dispensing events

CDMS

Data lock coordination

ICSR

Blinded AE reporting pathway

Compliant with

ICH E6(R3)

21 CFR Part 11